Operation Trial Blazer
This week, the US Department of Health and Human Services (HHS) announced a new initiative called ‘Operation Trial 1 Blazer’ that aims to bring back early-stage clinical research, which has increasingly been outsourced t…
Ruxandra Teslo
5 blurbs citing this writer/publication
A podcast wishlist for clinical trial reform
On a new episode of the Works in Progress podcast, Ruxandra Teslo, Ben Southwood and I chatted about everything you wanted to know about clinical trial reform — from why ethics reviews are so inefficient to how Australia…
A whiplash week for clinical trials
It’s been a big week for clinical trials. The FDA refused to review Moderna’s flu vaccine trial despite previously indicating their trial design was acceptable. Then, they reversed course . It’s unclear what prompted the…
Fixing IRBs without shortchanging research subjects
Institutional Review Boards (IRBs) are meant to protect research participants, but today their fragmented standards often create needless delays. In a new piece for the Institute for Progress, Ruxandra Teslo argues that …
In search of better surrogate endpoints
One reason clinical trials can take a long time is because it can take a long time to see how a patient’s condition turns out - some diseases have a slow progression. A good “surrogate endpoint” is a biomarker that relia…